Most of our titles are supported in Windows 10.
LINE OF DEFENSE
Compatible. See KB68 article for more.
LINE OF DEFENSE TACTICS
Some of our previous legacy games, though unsupported, can run under Windows 10.
You should however re-install DirectX Runtime, Visual Studio 2010, Visual Studio 2013 and the latest video & audio drivers.
If the title fails to run after following the above steps, try running the title in a windowed mode. See the KB40 article.